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Takayasu arteritis
1 OMIM reference -
3 associated genes
13 connected diseases
41 signs/symptoms
Disease Type of connection
Behçet disease
Mendelian susceptibility to mycobacterial diseases due to complete IL12B deficiency
Stevens-Johnson syndrome
Primary biliary cirrhosis
Williams syndrome
Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency
Early-onset autosomal dominant Alzheimer disease
Hereditary cerebral hemorrhage with amyloidosis, Arctic type
Hereditary cerebral hemorrhage with amyloidosis, Dutch type
Hereditary cerebral hemorrhage with amyloidosis, Flemish type
Hereditary cerebral hemorrhage with amyloidosis, Iowa type
Hereditary cerebral hemorrhage with amyloidosis, Italian type
Hereditary cerebral hemorrhage with amyloidosis, Piedmont type
Synonym(s):
(no synonyms)
Classification (Orphanet):
- Rare circulatory system disease
- Rare renal disease
- Rare systemic or rheumatologic disease
Classification (ICD10):
- Diseases of the musculoskeletal system and connective tissue -
Epidemiological data:
Class of prevalence: 1-9 / 1 000 000
Average age onset: adulthood
Average age of death: -
Type of inheritance: sporadic
External references:
1 OMIM reference -
1 MeSH reference: D013625
Gene symbol UniProt reference OMIM reference
HLA-B P30464142830
IL12B P29460161561
MLX Q9UH92602976
Very frequent
- Acute arterial hypertension / hypertensive crisis
- Acute ischemic syndrome
- Arterial aneurism (excluding aorta)
- Arterial pulse abolition
- Arterial stenosis / occlusion
- Asthenia / fatigue / weakness
- Cardiac valvulopathy
- Fever / chilling
- Hyperhidrosis / increased sweating
- Subcutaneous nodules / lipomas / tumefaction / swelling
- Vascularitis / vasculitides / arteritis
- Weight loss / loss of appetite / break in weight curve / general health alteration

Frequent
- Anaemia
- Angor pectoris / myocardial infarction
- Anorexia
- Aortic root dilatation / dilation / aneurysm
- Aortic valve atresia / stenosis / narrowing / supra-aortic / supra-valvular stenosis
- Arthritis / synovitis / synovial proliferation
- Biological inflammatory syndrome / increased erythrocyte sedimentation rate / CRP
- Cardiomyopathy / hypertrophic / dilated
- Chronic arterial hypertension
- Chronic skin infection / ulcerations / ulcers / cancrum
- Chronic uveitis / blepharitis / episcleritis / scleritis / conjonctivitis / keratitis
- Facial pain / cephalalgia / migraine
- Gangrena / necrosis
- Muscle weakness / flaccidity
- Myalgia / muscular pain
- Pulmonary hypertension
- Respiratory rhythm disorder
- Seizures / epilepsy / absences / spasms / status epilepticus
- Thoracic / chest pain
- Visual loss / blindness / amblyopia

Occasional
- Articular / joint pain / arthralgia
- Endocardium anomalies / fibroelastosis / endocarditis
- Hemoptysis
- Mesenteric / intestinal infarction
- Obnubilation / coma / lethargia / desorientation
- Retinopathy
- Speech troubles / aphasia / dysphasia / echolalia / mutism / logorrhea / dysprosodia
- Transient amaurosis / acute visual trouble
- Transient cerebral ischemia / stroke